PCR诊断对肺癌胸内分期的临床意义

The Capability of PCR Diagnosis on Staging of Bronchogenic Carcinoma

目的 分析评价X线胸片(PCR)对肺癌分期的能力。方法 对90例经组织学诊断确认的肺癌进行回顾性分析,与PCR诊断结果进行对比。结果 PCR对肺癌临床分期(cTNM)与病理分期(pTNM)相一致的占622%;判断可切除的和不可切除的肺癌准确性为733%。对不能手术的病例(533%)具有决定诊断意义的表现为主支气管罹病(T3、T4),胸水(T4),纵隔淋巴结转移(N2、N3)等;其次胸外转移和内科情况均为不能手术的重要前题。结论 PCR对肺癌分期的准确性较高,并且经济、简便,目前仍为临床诊断肺癌的首选检查方法。PCR的缺点是准确证实肿瘤浸润胸膜(壁)、纵隔(T3、T4)、纵隔淋巴结转移(N2、N3)及胸外转移(M1)等有一定限制。

Objective Study the capability of plane chest roentgenoscopy(PCR)in the staging of bronchogenic carcinoma.Methods Comparing PCR results with pathological diagnosis for 80 cases of bronchogenic carcinoma. Results The proportion of which PCR results are consistent with the pathological diagnosis is 62.2%;the accuracy of PCR on resesctable or unresectable for bronchogenic carcinoma is 73.3%.The criteria for unresesctable cases(53.3%)are mainbronchus being affected(T 3,T 4),thorax liquid(T 4),metastasis of carcinoma in mediastinum lymph mode(N 2,N 3)et al,metastasis of carcinoma out side the chest and some internal disease are criteria for unresectable as well. Conclusion The accuracy of PCR in the staging of bronchogenic carcinoma is high.This method is economy and convenient,and it is still the primary method for clinical diagnosis of bronchogenic carcinoma.The shortage of PCR are the uncertainty for some cases in demonstrating the tumor infiltration on pleura and mediastinum(T 3,T 4),metastasis of carcinoma in mediastinum lymph mode(N 2,N 3)and metastasis of carcinoma out side the chest et al. [