12例急性期HIV感染者抗病毒治疗结果分析

Analysis of prognosis of 12 HIV cases receiving antiretroviral treatment at an acute stage

目的初步探讨急性期艾滋病病毒(HIV)感染者进行抗病毒治疗(ART)对其预后的影响。方法对在佑安医院接受抗病毒治疗的12例急性期HIV感染者进行跟踪随访和分析。结果 12例HIV感染者均在感染6个月内开始ARV治疗,并坚持服药未中断治疗,随访治疗期6个月-3年。治疗后3个月内检测病毒载量均低于最低检测限,1年后CD4+T细胞数均>500/μL,无明显严重药物不良反应发生,HIV感染者生存状态良好。结论初步结果显示,急性期开始抗病毒治疗可能为艾滋病病人带来好的预后结果。

Objective To explore the prognosis of HIV cases receiving early antiretroviral （ARV） treatment at an acute stage or stage of primary infection. Method Twelve HIV cases who received early antiretroviral treatment at a stage of primary infection were followed up and.analyzed. Result Twelve HIV cases were given anti-retrovi ral treatment within six months after primary infection,and were followed up for 6 months to three years, and none of them stopped treatment. In 3 months after the treatment HIVRNA loads （VL） were under lower detection level （LDL）and CD~ T cell counts rose to above 500μl,no serious side effect occurred and life quality was improved in all the 12 cases. Conclusion Primary results have shown that the antiretroviral treatment will bring good prognosis for HIV cases if early antiretroviral treatment is given at a stage of primary infection.