摘要
目的:探讨2型糖尿病(DM2)患者糖化血红蛋白(HbA1C)与血清E-选择素之间的相关性。方法:用高压液相色谱法检测HbA1C和酶联法检测E-选择素,分析61例DM2患者及35名正常健康人作对照的血浆HbA1C与血清E-选择素间的相关性。结果:DM2患者HbAlC水平与E-选择素水平均非常显著地高于正常人组(P<0.01),且HbA1C水平与E-选择素水平呈显著正相关(r=0.5714,P<0.01)。结论:高血糖对血清E-选择素的表达可能有促进作用。
Objective To observe the correlation between blood HbA1C and E-selectin levels in patients with DM2. Methods Blood glycosylated haemoglobin (HbA1 C)(with high-pressure liquid ehromatograply) and serum E-selectin (with ELISA) levels were determined in 61cases of DM2 and 35 normal controls. Results Blood HbA1 C, serum E-selectin levels were remarkably higher than those in controls (P 〈 0.01 ), blood HbA1 C level was obvious positively correlated with serum E-selectin (r = 0.5714,P 〈 0.01 ). Conclusion High blood glucose might promote the expression of serum E-selectin in patients with DM2.
出处
《放射免疫学杂志》
CAS
2012年第3期326-327,共2页
Journal of Radioimmanology
关键词
2型糖尿病
糖化血红蛋白
E-选择素
type-2 Diabetes(DM2), glycosytated haemoglobins( HbAlc), E-Selectin