不明原因发热的临床综合诊断

The Comprehensive Clinical Diagnosis of Fever of Unknown Origin

不明原因发热是临床常见疑难疾病,其定义随着疾病种类的不断变化及诊断流程的进步而逐步完善。不明原因发热(feverof unknown origin,FUO)病因包括感染性疾病、风湿免疫性疾病及肿瘤性疾病三大类,三大病因各自具有不同临床特征。详细病史采集、全面体格检查及常规实验室检查对诊断FUO至关重要,必要时应及时进行相关影像学及病理学检查,疾病的最终诊断应综合分析病史及实验室检查。

Fever of unknown origin is a common clinical difficult and complicated diseases.Its definition has been gradually improved with the changing of the type of illness and the progress of the diagnostic process.The main causes of FUO include infectious diseases,rheumatoid autoimmune diseases and neoplastic diseases.The three major causes have different clinical features.Detailed history taking,comprehensive physical examination and routine laboratory tests are essential in the diagnosis of FUO.Imaging and pathological examination should be taken in timely.The final diagnosis of the disease should be a comprehensive analysis of medical history and laboratory tests.