光泽苔藓的共聚焦激光扫描显微镜下特征

The Features of Lichen Nitidus under Confocal Laser Scanning Microscopy

目的对光泽苔藓的共聚焦激光扫描显微镜(CLSM)特征进行初步探索。方法选取在本院就诊的27例临床诊断为光泽苔藓的患者,每位患者挑选一处皮损先行CLSM检查,后取该处皮损行常规组织病理检查。同时在该皮损附近正常皮肤处行CLSM检查,进行对照。结果与周围正常皮肤相比,皮损处CLSM图像可观察到真皮乳头部散在分布局限性炎细胞浸润灶,其主要由组织细胞和淋巴细胞组成,下延的表皮突环抱浸润灶。结论光泽苔藓的CLSM图像有一定的特征性,可为该病的诊断和鉴别诊断提供有效的帮助。

Objective To explore the preliminary featuers of lichen nitidus under confocal laser scanning microscopy （CLSM）. Methods Twenty-seven patients with a clinical diagnosis of lichen nitidus in our hospital were selected. The same tissues from skin lesions were analyzed by CLSM and conventional histopathologie exami- nation. The normal skin adjacent to lesions were also examined by CLSM for contrast. Results Compared with the surrounding normal skin, focal infiltrations in dermal papilla could be observed from the images of skin lesions under CLSM,which were mainly composed Of histocytes and lymphocytes. Besides,the troehan- terellus stretches downward and encircles the infiltration foci. Conclusion The CLSM images of Lichen Nit- idus show defitite characteristics,which can effectively help diagnosis and differential diagnosis of this disease. However, due to the limited number of cases, the complete features of CLSM images of lichen nitidus still need further investigation and exploration.