生精片治疗精液不液化100例临床研究

Shengjing Tablets for semen non-liquefaction:A clinical study of 100 cases

目的:研究生精片治疗精液不液化的疗效,探讨其可能机制,寻求一种治疗精液不液化的有效药物。方法:150例精液不液化患者,随机分为治疗组100例,对照组50例,分别口服生精片和维生素E胶囊,45 d为1个疗程,连续观察2个疗程,记录精液液化时间及其他参数变化情况。结果:1个疗程后,治疗组痊愈68例,有效20例,无效12例;2个疗程后痊愈84例,有效9例,无效7例,治愈率(痊愈+有效)达93.0%;对照组2个疗程后痊愈8例,有效8例,无效34例,与对照组比较有统计学差异(P<0.01)。同时生精片可以显著提高精子密度和精子活力。结论:生精片可显著缩短精液液化时间,临床治疗精液不液化效果显著,安全可靠。

Objective： To investigate the efficacy and action mechanism of Shengjing Tablets in the treatment of semen non-liquefaction. Methods： We randomly assigned 150 patients with semen non-liquefaction to receive Shengjing Tablets （treatment group, n = 100） and vitamin E capsules （control group, n =50） for 2 courses of 45 days each, followed by observation of the seminal liquefaction time and other semen parameters. Results ： After the first course, 68 of the patients in the treatment group were cured, 20 responded and 12 failed to respond; and after the second course, 84 were cured, 9 responded and 7 failed to respond, with an effec- tiveness rate of 93.0%. In comparison, only 8 of the controls were cured, 8 responded and 34 failed to respond after the 2 courses of medication. There were statistically significant differences between the two groups （ P 〈 0.01 ）. Meanwhile, the treatment group showed obvious improvement in sperm motility and concentration. Conclusion ： Shengjing Tablets may shorten the time of seminal liq- uefaction, and can be used as a safe and effective therapy for semen non-liquefaction.