医院船就诊拉美3国人群中慢性肾脏疾病与脂质代谢的关系研究

Relation of chronic kidney disease and lipid metabolism among three Latin American countries' outpatients in hospital ship

目的:探讨医院船就诊的拉美3国人群慢性肾脏疾病(CKD)与脂质代谢的关系。方法:选取2011-10～11医院船执行任务期间在医院船就诊的拉美3国体检人员692人(年龄均超过18岁),记录上述患者性别、年龄、尿蛋白、尿红细胞、血肌酐、血尿素氮、血胆固醇、血甘油三酯,并根据年龄、血肌酐计算肾小球滤过率(GFR)。结果:CKD患病率16.3%(113/692),血脂异常、高TC血症及高TG血症患病率分别为46.2%、22.8%、35.8%;血脂异常患者中CKD患病率(20.3%)高于血脂正常患者(12.9%),高TG血症患者CKD患病率(24.2%)高于TG正常患者(11.9%),且有统计学意义(P<0.05);CKD患者中血脂异常、高TG血症患病率明显高于非CKD患者(P<0.05)。结论:拉美3国门诊体检人员中CKD、血脂异常患病率高,CKD患者血脂异常比例明显升高,以TG升高为主,血脂异常患者CKD患病率高。

Objective：To investigate the relation of chronic kidney disease （CKD） and lipid metabolism in three Latin American countries＇ outpatients in hospital ship. Methods： A total of 692 cases from three Latin American countries who made health examination from October to November 2011 in hospital ship were selected. The gender, age, proteinuria, hematuria, serum creatinine, serum urea nitrogen, serum total cholesterol, and serum triglycer- ide were analyzed, the glomerular filtration rate （GFR） of the outpatients was calculated according to their age and the levels of serum creatinine. Results：The prevalence of CKD was 16.3%. The prevalence of dyslipidemia, hy- percholesterolemia and hypertriglyceridemia were 46.2%, 22.8%, and 35.8% respectively. The prevalence of CKD in dyslipidemia and hypertriglyceridemia outpstients were higher than those in normal lipid and normal triglyc- eride outpstients, respectively（P 〈0.05）. The prevalence of dys//pidemia and hypertr/glyceridemia in CKD outp- stients were higher than those in non - CKD outpstients （ P 〈 0.05 ）. Conclusion： The prevalence of CKD and dys- lipidemia was higher in three Latin American countries＇ outpatients. The prevalence of CKD was higher in the dys- lipidemia＇s patients.