微种植钉表面含银羟基磷灰石涂层的制备及溶血试验

The Preparation of the Nanosilver-containing hydroxyapatite coatings on the surface of the titanium miniscrew and its haemolysis test

目的:在微种植钉表面制备纳米银羟基磷灰石(HAp/nanosilver)涂层,并检验涂层的溶血率。方法:采用电化学沉积的方法在微种植钉表面上制备HAp/nanosilver涂层并给予表征,同时进行溶血试验,检测含该涂层的种植钉的血液相容性。结果:成功制备出含纳米银羟基磷灰石涂层的微种植钉,表征的HAp/nanosilver涂层溶血率为1.15%,小于5%,符合材料溶血要求。结论:含银羟基磷灰石涂层不会引起急性溶血反应,具有良好的血液相容性。

Objetive： To preparate the Nanosilver-containing hydroxyapatite coatings on the surface of the titanium miniscrew and investigate its haemolysis rate. Method：The electrochemical deposition technology was adopted to construct the Nanosilver-containing hydroxyapatite coatings on the surface of the titanium miniscrew and to characterise it, then use the flash rabbit blood to do the haemolysis test. Result： The haemolysis rate of the characteristic Nanosilver-containing hydroxya- patite coatings is 1.15 %, and it complys to the requirements of less than 5 %. Conclusion：The Nanosilver-containing hydroxyapatite coatings will not induce acute haemolysis.it has a good blood compatibilty.