薁并[2，1-b]吡啶的简便合成方法

A simple method for the synthesis of azuleno [2,1-b] pyrines

以2-氨基-1-乙酰基薁-3-甲腈和β-二羰基化合物为原料,在1-甲基咪唑-3-丙基磺酸硫酸氢盐的作用下,一锅法合成了薁并[2,1-b]吡啶类衍生物。该反应收率良好、操作简单、条件温和。产物的结构通过红外光谱、核磁共振谱和元素分析证实。

Azuleno [ 2,1 -b ] pyridins were synthesized by con- densation of 3-acetyl-2-aminoazulene-1 -carbonitrile with β-di- carbonyl compounds in the presence of 1-methyl-3-（3-sulfo- propyl） imidazolium hydrogen sulfate with good yields. All the compounds were confirmed by I HNMR, IR and elemental analysis.