SYNTAX积分预测冠心病复杂病变患者经皮冠状动脉介入治疗预后的作用

Role of SYNTAX score in predicting prognosis of patients with complex coronary heart disease after percutaneous coronary intervention

目的评价SYNTAX积分对冠心病3支病变和(或)左主干病变患者PCI预后的作用。方法经冠状动脉造影证实的3支病变和(或)左主干病变并接受PCI的患者1 90例。对每例患者造影结果进行SYNTAX评分,SYNTAX评分按三分位数分为:低分组、中分组和高分组,通过门诊或电话随访患者主要不良心脑血管事件(MACCE)。结果经PCI的冠心病3支病变和(或)左主干病变190例患者中,29例出现MACCE,发生率为15.3%。SYNTAX积分低分组、中分组及高分组的MACCE发生率分别为9.1%、1 6.2%及30.9%。Cox多因素分析显示,SYNTAX积分HR=2.07,95%CI:1.25～3.44,差异有统计学意义(P=0.005)。结论 SYNTAX积分是预测PCI预后的较理想工具,该积分系统也适用于我国冠心病3支病变和(或)左主干病变患者PCI术后预后的预测。

Objective To assess the role of SYNTAX score in predicting the prognosis of patients with triple vessel lesion and/or left main coronary artery lesion after percutaneous coronary intervention（PCI）. Methods One hundred and ninety patients with coronary arteriography-confirmed triple vessel lesion and/or left＇ main coronary artery lesion after PCI were scored with the SYNTAX scoring system according to their coronary arteriographic findings. The patients were followed up by telephone or at outpatient department to find their major adverse cardiocerebral events（MACCE）. Results Among the 190 patients, MACCE occurred in 29, accounting for 15.3%. Multivariate Cox regression analysis showed that the incidence of MACCE was 9. 1%, 16.2% and 30.9%, respectively, in patients with a low, moderate, and high SYNTAX score （HR=2.07,95%CI.1.25-3.44,P=0. 005）. Conclusion SYNTAX score can predict the prognosis of patients with triple vessel lesion and/or left main coronary artery lesion after PCI.