扁桃体Burkitt淋巴瘤1例伴文献复习

A report of one case of Burkitt lymphoma and literature review

目的探讨Burkitt淋巴瘤的临床、病理特点及可能的病因。方法分析1例扁桃体Burkitt淋巴瘤的临床及病理资料,并结合文献复习。结果肿瘤细胞弥漫分布,中等大小、相对单一,星空图像可见,核分裂象多见。免疫组化:CD20+,CD10+,PAX5+,Bcl-6+,MuM1-,Bcl-2-,C-Myc消化过度,Ki-67+(约100%)。结论对Burkitt淋巴瘤的诊断需结合镜下图像及免疫组化,必要时进行基因重排。

Objective To investigate the clinical, pathological characteristics and possible causes of Burkitt lymphoma（ BL ）. Methods Clinic-pathological data of one case of BL were analyzed. Combined with literatcure review. Results The tumor cells had diffused distribution with medium-size and relatively homogeneous character, much nuclear divisions were seen. ＂Sky＂ image was visible. Immuno- histochemistry showed ： CD20 ＋ , CD10 ＋ , PAX5 ＋ , Bcl-6 ＋ , MuMl - , Bcl-2 - , and the positive rates of Ki-67 were about 100%, C-Myc protein was digested excessively. Conclusion The diagnosis of Burkitt lymphoma should be combined with the microscopic images and immunohistochemistry,and gene rearrangement was in need when necessary.