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早产儿甲状腺功能低下研究 被引量:11

STUDY ON THE HYPOTHYROIDISM OF PREMATURE BABY
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摘要 目的观察不治疗的早产儿甲状腺功能低下是否会影响其生长发育。方法将住院的早产儿出生后3天查甲功三项(TSH、FT3、FT4),正常者为正常组;FT3、FT4低下者随机分成治疗组及观察组;三组各30例,定期复查甲功三项并进行生长发育监测2年,采用Bayley婴儿发育量表进行智能测定,结果以发育商(DQ)表示。结果正常组、治疗组及观察组患儿的DQ低下分别为2例(6.7%)、2例(6.7%)及9例(30%);身高、体重及头围生长落后均为分别4例(13.3%)、3例(10%)及5例(16.6%);黄疸消退延迟分别为4例(13.3%)、5例(16.6%)及5例(16.6%);腹胀分别为9例(30%)、12例(40%)及8例(26.6%);前囟闭合延迟分别为2例(6.7%)、3例(10%)及2例(6.7%);三组患儿出牙时间均无异常。三组的DQ低下发生率差异有统计学意义(p<0.05),三组身高、体重、头围生长发育落后、黄疸消退延迟、腹胀、前囟闭合延迟发生率差异均无统计学意义(p>0.05)。正常组DQ为(98.4±4.5),明显高于观察组的(92.5±8.3),p<0.01;治疗组DQ为(96.7±5.6)高于观察组的(92.5±8.3),p<0.05;正常组DQ与治疗组DQ差异无统计学意义(p>0.05)。结论不治疗的早产儿甲状腺功能低下会影响其生长发育。
出处 《现代医院》 2012年第6期69-70,共2页 Modern Hospitals
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