腹型紫癜患儿病程中肠系膜上动脉彩色多普勒血流参数变化

The Doppler parameters changes of superior mesenteric artery in children with abdominal type Henoch-Schonlein purpura

目的观察腹型紫癜患儿病程中肠系膜上动脉彩色多普勒血流参数变化有无规律。方法测量10例腹型紫癜患儿急性期、恢复期肠系膜上动脉彩色多普勒血流参数,包括收缩期峰值流速、舒张末期流速、阻力指数,并与17名体检健康儿童比较。结果腹型紫癜组患儿急性期肠系膜上动脉收缩期峰值流速为(41.57±8.02)cm/s,恢复期为(33.38±7.44)cm/s,健康对照组儿童为(35.34±9.73)cm/s,三者之间的差异无统计学意义(F=2.471,P=0.10);腹型紫癜组患儿急性期肠系膜上动脉舒张末期流速为(7.63±4.28)cm/s,高于恢复期的肠系膜上动脉舒张末期流速(4.23±2.57)cm/s和健康对照组儿童的肠系膜上动脉舒张末期流速(3.77±0.87)cm/s,且差异均有统计学意义(t=0.066,P=0.025;t=0.059,P=0.003);腹型紫癜组的患儿急性期肠系膜上动脉阻力指数为(0.85±0.17),低于恢复期的肠系膜上动脉阻力指数(1.00±0.15)和健康对照组儿童的肠系膜上动脉阻力指数(1.04±0.13),差异也均有统计学意义(t=1.391,P=0.020;t=1.239,P=0.026)。结论在腹型紫癜患儿病程中,肠系膜上动脉彩色多普勒血流参数变化有规律,可用于评估腹型紫癜病情变化。

Objective To study the changes of flow parameters of superior mesenteric artery （SMA） in children with abdominal type Henoch-Schonlein purpura （HSP） using color Doppler ultrasound.Methods Ten children with abdominal type HSP and 17 controls were included in present study.The blood flow parameters of SMA[including peak velocity（PV）,end-diastole velocity（EDV）,resistant index（RI）]were measured at acute and recovery stage separately.Statistical analysis was conducted among groups.Results PV were （41.57±8.02）cm/s,（33.38±7.44）cm/s and （35.34±9.73）cm/s in acute stage,recovery stage and control group,respectively.There was no statistically significant difference among groups（F=2.471,P=0.10）.EDV were（7.63±4.28）cm/s,（4.23±2.57）cm/s and （3.77±0.87） cm/s in acute stage,recovery stage and control group,respectively.There was significantly significant differences between acute stage group and other two groups（t=0.066,P=0.025;t=0.059,P=0.003）.RI were （0.85±0.17）,（1.00±0.15） and （1.04±0.13） in acute stage,recovery stage and control group,respectively.Also there was significantly significant differences between acute stage group and other two groups（t=1.391,P=0.020;t=1.239,P=0.026）.Conclusion For abdominal type HSP in children,the changes of PV,EDV and RI of SMA were significant,which may help us determine the stage of disease.