和中平逆方治疗肝胃郁热型反流性食管炎临床研究

The Clinic Study on Curative Effect of the He Zhong Ping Ni Prescription in Treating Liver Stomach Heat Accumulation Syndrome of Reflux Esophagitis(RE)

目的:观察和中平逆方治疗肝胃郁热型反流性食管炎的临床疗效。方法:选择60例经内镜检查及中医辨证确诊为肝胃郁热型的反流性食管炎患者,分为中药治疗组、西药对照组,每组各30例,均以8周为一疗程,疗程结束后进行疗效比较。结果:两组临床症状疗效,治疗组总有效率为96.67%,对照组为96.66%,两组比较无显著性差异(P>0.05);内镜疗效,治疗组总有效率为73.33%,对照组为73.33%,两组比较无显著性差异(P>0.05);肝胃郁热证候疗效,治疗组总有效率为96.67%,对照组为76.67%,两组比较有显著性差异(P<0.05)。结论:1.和中平逆方对反流性食管炎的症状、食管黏膜炎症改善均有明显疗效;2.和中平逆方对肝胃郁热型反流性食管炎中医证候的改善优于奥美拉唑肠溶胶囊。

Objective： To observe the clinical effect on liver stomach heat accumulation illness of Reflux esophagitis（RE） cured by the treatment of the Hezhong Pingni decoction.Methods： A randomized controlled trial designed with 60 patients were divided into Chinese medicine test group（n=30） and the omeprazole controlled group（n=30） by endoscopy and traditional Chinese medicine dialectical method,treatment for 8 weeks.We will get the assessment of the improvement of RE symptom in the pre-treatment and post-treatment.Results： The total effective rate of improvement of symptoms was 96.67 % in test group,and 96.66 % in the controlled group;there was no significant difference（P〉0.05） between test group and controlled group.The total effective rate of endoscopic treatment was 73.33 % in the test group,and also 73.33 % in the controlled group;there was no significant difference（P〉0.05）.The total effective rate of improvement of liver stomach heat accumulation illness was 96.67% in the test group,but 76.67% in the controlled group;there was significant difference between test group and controlled group（P〈0.05）.Conclusion： 1.The results showed the test group and the controlled group have a remarkable effect in improving the symptoms of RE.2.The improvement of liver stomach heat accumulation syndrome of RE in the test group is superior to that in the controlled group.