应用动态血压探讨高血压病血压变化与脑血管突发事件的关系

Application of ambulatory blood pressure monitoring to study the relationship between blood pressure changes and cerebralvascular attack in hypertensives

目的探讨高血压病患者动态血压与脑血管突发事件的关系。方法对1200例高血压病患者进行24小时动态血压测定并追踪随访，对后来发生脑血管突发事件的148例患者的动态血压变化与发生脑梗死、脑出血的关系进行研究；并随机选择100例来发生脑血管突发事件的高血压病患者作比较。结果脑梗死组及脑出班组共同点是收缩压呈持续升高，负荷值增大，血压夜间下降率均＜10％，呈非构形改变。与对照组比较差异呈显著性。结论高血压病患者动态血压变化与脑血管突发事件的发生有关。

Objective To study the relationship between ambulatory blood pressure hypertension and cerebralvascular attack(CA) in patients of hypertension. Methods 1200 cases of hyperiension received 24-hour ambulatory blood monitoring(ABPM ), and follow-up visits were carried. 148 cases of CA, who were later complicated with cerebral infarction(CI)or cerebralhemorrhage(CH), were analyzed concerning their changes of ABPM, and were compared with the control group of lo() caseswithout CA. Results In the groups of CI and CH, syslolic pressure and its loading values were increased continually, and thedecrease rate in systolic and diastolic blood pressure was less than lo%. There was signilicant difference compared with thecontrol group. Conclusion The variability of ambulatory blood pressure in hypertension was closely related to cerebralvascularattack.