乙型肝炎发病及复发与心理社会因素的关系

A Study on Relation between Onset/recurrence of viral Hepatitis B and Psychosocial factors

为研究乙型肝炎 (HepatitisB ,HB)发病及复发与社会心理因素的关系 ,对 85例急性乙肝炎 (AcuteHepatitisB ,AHB)患者、6 7例慢性乙型肝炎 (ChronicHepatitisB ,CHB)患者采用生活事件量表 (LES)、艾森克个性问卷 (EPQ)、症状自评量表(Scl- 90 )进行问卷调查。结果显示HB病人的生活事件单位(LEU)明显高于正常人 (P <0 0 0 1) ,并在CHB组和男性患者中明显增高。EPQ测定CHB组在精神质、神经质方面明显异常 (P <0 0 5 )。Scl- 90测定CHB组的多项得分高于AHB组和对照组 (P <0 0 5～P <0 0 1)。提示 :社会心理负荷过重是HB发病及复发的诱因之一 ;CHB患者具有个性异常和心理健康水平低下的特点 。

In order to study the relation between the onset/recurrence of viral hepatitis (VH),152 cases with hepatitis B(HB) who were admitted in our hospital the during the first of april-17th of june 1997,were investigated of them 85 cases were acute hepatitis B(AHB),67 cases were chronic hepatitis B(CHB),besides,50 healthy bodies were control group.The survey item:Life evens scale(LES),Eysenck personality questionnaire(EPQ)and symptoms check list 90(Scl-90).The results show that in HB group the life events unit(LEU)was obviously higher than those in control group(P<0 001).The main life evens were suffering form greater pressure in the respect of study and work,and problems and trouble concerned with family,marrige and youngers.Above two conditions presented greater proportion,there constituted proportion was approximate 25 45 percent and 20 79 percent,respectively.The value of LEU was markedly higher in CHB group and in male cases than those in AHB group,control group and female cases(P<0 05),respectively.In the measurement of EPQ the score of nervousness(N) and psychoticism (P) in CHB group were obviousiy higher than those in AHB group and control group respectively(P<0 05),were no obvious difference was found between the AHB group and control group.Concerning Scl-90 in cases with CHB,four factor scores of somatization,depression,anxiety,and psychotism were obviously higher than those in the AHB group and chinese normal sample.Conclusion:Psychosocial overload is an inducement of the onset/recurrence of HB.Patients with CHB present abnurmality of personaliti,in them psychical healthy level is loewr,and are high risk masses,to them psychological measure is needful to intervene.