48例小儿心脏术后体外膜肺氧合临床结果分析

Clinical outcomes with extracorporeal membrane oxygenation support in 48 pediatric patients after cardiac surgery

目的:对阜外医院小儿心脏手术后,不同适应症下实施体外膜肺氧合(ECMO)治疗的效果及并发症情况进行分析,为更好的把握ECMO的临床适应症提出依据。方法:回顾性分析2004年12月至今48例小儿心脏术后ECMO的临床资料。结果:患儿年龄5 d～6岁;体质量3～17 kg。48例中脱离ECMO 30例(62.5%),最终治愈出院24例(50%)。心、肺功能持续不恢复及后期继发的急性肾衰竭是导致死亡的主要原因。结论:适应症的选择及治疗期间的并发症决定了ECMO总体的治疗效果。

Objective：The purpose of our research was to study the clinical outcomes of children with congenital heart disease（CHD） requiring extracorporeal membrane oxygenation（ECMO） support after cardiac surgery at Fu Wai hospital.Methods：We retrospectively reviewed the medical record of 48 children requiring ECMO support from Dec.2004 to now.Results： Patients age ranged from 5 day to 6 years and body weight ranged from 3 to 17kg.30 children（62.5%） were successfully weaned and 24（50%） survived to discharge.Inability to separate from ECMO support and the development of acute renal failure may have an increased risk of death.Conclusion：The overall treatment outcomes depends on the selection of indication and the complications during ECMO.