心理干预对缓解艾滋病患者高效抗反转录病毒治疗过程中焦虑的效果

Study of psychological intervention on alleviating anxiety of patients during high active antiretrovirtal therapy

目的探讨心理干预对艾滋病（AIDS）患者高效抗反转录病毒治疗中产生焦虑症状的缓解效果。方法40位符合入组条件的AIDS患者，按随机数字表法分为干预组和对照组各20例。对照组按常规护理，干预组在此基础上进行心理干预，分别在干预前后对两组患者采用焦虑自评量表测量。结果干预组在干预前SAS粗分为（48．8±1．8）分，干预后（36．8±1．7）分，差异有统计学意义（f=4．8250，P〈0．01）；对照组在干预前SAS粗分为（49．4±1．96）分，干预后（49．2±1．9）分，差异无统计学意义（t=0．0731，P〉0．05），两组干预后的SAS粗分比较，差异有统计学意义（t=-4．8601，P〈0．01）。干预后干预组的依从性及随访规律性均提高，差异有统计学意义（P〈0．05或P〈0．01）。结论AIDS患者经过心理干预后焦虑水平以及焦虑程度均有不同程度的缓解，心理干预可有效缓解AIDS患者的心理焦虑。

Objective To explore the effect of psychological intervention on the alleviating anxiety of patients on high active antiretroviral therapy （HAART）. Methods Forty AIDS patients were recruited and were randomly divided into the treatment group （n = 20） which received psychotherapy, and control group（ n = 20） which received traditional care. Self-rating anxiety scale （SAS）was used to investigate patients before and after intervention. Results The SAS score of the treatment group before intervention （48. 8 ± 1. 8 ） was significantly higher than that after the intervention （ 36.8 ± 1.7 ）, （ t = 4. 825 0, P 〈 0. 001 ）. No difference was found in the SAS score in control group before（49.4 ±1.96） and after（49.2 ±1.9） the intervention（t =0. 073 1, P 〉0. 05）. After intervention, the SAS score of intervention group was lower than that of control group （t = -4. 860 1 ,P 〈0.01 ） ,and the adherence, follow-up compliance of treatment group were significantly improved （P 〈 0. 05 or P 〈 0. 01 ）. Conclusions Psychological intervention can effectively alleviate the anxiety of patients on HAART.