痰热清联合利巴韦林治疗小儿疱疹性咽峡炎的临床观察

The Clinical Observation of Tanreqing Combined with Ribavirin Treatment in Children with Herpetic Angina

目的:观察痰热清注射液联合利巴韦林注射液治疗小儿疱疹性咽峡炎的临床疗效。方法:将58例疱疹性咽峡炎患儿随机分为两组。观察组30例,应用痰热清注射液0.3～0.5 mL/(kg.d)联合利巴韦林注射液每次10～15 mg/kg静脉滴注,1次/d,疗程3～5 d;对照组28例,单独应用利巴韦林注射液静脉滴注。两组对症治疗相同,合并细菌感染者加用抗生素治疗。结果:观察组总有效率93.33%高于对照组78.57%(P<0.05),两组退热时间、恢复进食时间、疱疹消退时间、病程比较观察组均优与对照组(P<0.01)。结论:痰热清注射液联合利巴韦林注射液治疗小儿疱疹性咽峡炎疗效满意。

Objective：To investigate clinical curative effect of Tanreqing injection combined with ribavirin injection in the treatment of children with herpetic angina. Methods： Together 58 cases of herpetic angina were randomly divided into two groups. The observation group of 30 cases were given 0. 3 - 0.5 mL/（ kg · d ） Tanreqing injection combined with 10 -15 mg/kg ribavirin injection intravenously, once daily for 3 - 5 days. The control group of 28 cases only received ribavirin injection. Results： The total effective rate of observation group （93.33%） was significantly higher than that of control group （78.57%） （P〈0.05）. The time to deferveseence, the appetite recovery time, herpes subside time, course of disease in the observation group were shorter than those in the control group （P〈0. 01）. Conclusions： The effect of Tanreqing injection combined with ribavirin injection in the treatment of children with herpetic angina is satisfactory.