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慢性肾脏病患者高磷血症的治疗 被引量:15

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摘要 慢性肾脏病(CKD)在全球有很高的患病率和死亡率,我国慢性肾脏病总患病率达10.8%,约50%的终末期肾病透析患者有不同程度的心脑血管疾病,在终末期肾衰竭维持血透的患者中因心脑血管疾病导致的死亡率高达50%以上。高磷血症可以促进甲状旁腺素(PTH)分泌,导致慢性肾脏病一矿物质和骨异常(CKD-MBD),增加成纤维细胞生长因子-23(FGF-23)的水平,促进血管钙化,增加心血管事件的发生,
作者 彭鲲 王莉
出处 《临床内科杂志》 CAS 2012年第5期302-304,共3页 Journal of Clinical Internal Medicine
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