围生期孕妇血清D-二聚体浓度检测及分析

Detection and Analysis of Serum D-Dimer Contents in Pregnant Women in Perinatal Period

目的:探讨围生期孕妇血清D-二聚体浓度的变化。方法:采用胶乳增强免疫比浊法在日立7600-020全自动生化分析仪上测定160例围生期孕妇和50例正常非孕妇女的血清D-二聚体浓度,同时在CA-1500血凝分析仪上对上述人员进行PT、APTT测定,并对结果进行分析。结果:围生期孕妇血清D-二聚体与正常非孕妇相比,有不同程度升高(P<0.01)。结论:对围生期孕妇血清D-二聚体浓度进行监测,对于及时发现妊娠高血压综合征、预防弥散性血管内凝血的发生和及时治疗有重要意义。

Objective ：To investigate the changes of serum D -Dimer in pregnant women in perinatal period. Methods： 160 pregnant women in perinatal period and 50 healthy non - pregnant women were selected. Serum D - Dimer with immunoturbidimetry were tested by HITACHI 7600 -020, and PT,APTF were tested by sysmex corporation CA - 1500. Results：Plasma serum D - Dimer levels showed significant differences between the pregnant women in perinatal period and the healthy non - pregnant women. Conclusion ：Monitoring the serum D - Dimer levels of the pregnant women in perinatal period has important significance in detecting pregnancy hypertension and preventing disseminated intravascular coagulation（DIC）.