摘要
目的:观察糖皮质激素继发糖尿病(类固醇糖尿病)的血糖水平变化特点。方法:对116例被诊断为类固醇糖尿病的药疹患者和与之相匹配的普通2型糖尿病患者进行动态血糖水平监测,评价并比较两组患者间血糖水平变化的特点和差异。结果:类固醇糖尿病患者以午餐后至睡前血糖水平升高为主要表现,空腹血糖水平一般正常,而2型糖尿病患者的全天平均血糖水平及其波动和低血糖症发生率均低于类固醇糖尿病患者,全天血糖水平达标时间明显长于类固醇糖尿病患者。结论:类固醇糖尿病患者的血糖水平变化具有自身的临床特点,与普通2型糖尿病患者的血糖水平变化明显不同,其血糖水平变化与激素作用高峰有关,临床干预中应注意这一特点并采取相应措施。
Objective: To observe the blood glucose changes of the secondary diabetes caused by glucocorticoid (steroid diabetes). Methods: The continuous glucose levels of 116 drug eruption patients who were diagnosed as the steroid diabetes and of the same number of the normal patients with type 2 diabetes matched were monitored, and evaluated to compare their characteristics and the difference. Results: In the steroid diabetes, the main clinical manifestation was the blood glucose rise after lunch to bedtime, and the fasting blood glucose was normal. While in type 2 diabetes, the average of blood glucose, blood glucose fluctuations, low blood sugar were all lower than those of the steroid diabetes. The time of all-day blood glucose levels which reached the standard indicator was longer than that of the steroid diabetes, which there was a statistically significant difference between the two groups. Conclusion: The steroid diabetes had its own blood glucose changes in the clinical feature that they were significantly different from the type 2 diabetes. The peak effects of glucocorticoid were responsible for the glucose changes. We should pay attention to this characteristic in the steroid diabetes and take the appropriate measures.
出处
《上海医药》
CAS
2012年第6期11-13,共3页
Shanghai Medical & Pharmaceutical Journal