期刊文献+

“通腑泻热合剂”灌肠联合西医常规方法治疗肺挫伤30例临床研究

下载PDF
导出
摘要 目的:观察通腑泻热合剂灌肠联合西医常规治疗对肺挫伤患者的临床疗效及对血清肿瘤坏死因子α(TNF-α)、白介素8(IL-8)的影响。方法:将60例肺挫伤患者随机分为治疗组和对照组各30例,治疗组给予常规治疗和通腑泻热合剂灌肠治疗,对照组给予常规治疗和等量生理盐水灌肠治疗,观察2组临床疗效和治疗前后血清中TNF-α、IL-8的变化。结果:治疗后治疗组临床评分明显低于对照组,肺部感染、ARDS发生率明显低于对照组;2组治疗后TNF-α、IL-8水平均降低,治疗组明显低于对照组。结论:通腑泻热合剂对肺挫伤有明显的临床疗效,能减轻肺挫伤患者的炎症反应,降低肺组织损害,其作用机制可能是通过对TNF-α和IL-8的免疫调节实现的。
出处 《江苏中医药》 CAS 2012年第6期18-20,共3页 Jiangsu Journal of Traditional Chinese Medicine
基金 广州中医药大学2008年科研创新基金资助(08CX33)
  • 相关文献

参考文献3

  • 1李辉,主编.现代胸外科急症学.北京:人民军医出版社.2006.604.
  • 2徐志飞,刘军强.肺挫伤研究现状及治疗[J].创伤外科杂志,2005,7(2):81-84. 被引量:54
  • 3Fujishima S,Sasaki J,Shinozawa Y,et al.Interleukin 8 in ARDS.Lanct, 1993,342(8865) :237.

二级参考文献22

  • 1何家庆,蒋耀光,王如文,蹇华胜,吴秋平,陈淑芳,温建良,罗香国,于长青.家兔肺挫伤早期影像学的变化及其意义[J].创伤外科杂志,2004,6(6):444-447. 被引量:5
  • 2Gary S.Allen,Charles S.Cox.Pulmonary contusion in children:diagnosis and management[J].Southern Medical Journal,1998,91(12):1099-1106.
  • 3Wang ND,Stevens MH,Doty DB.Blunt chest trauma:an experimental model for heart and lung contusion[J].J Trauma,2003,54(4):744-748.
  • 4Cohn SM,Stephen M.Pulmonary contusion:review of the clinical entity[J].J Trauma,1997,42(5):973-979.
  • 5Alex Blentsch,Peter A Ward.Regulation of experimental lung inflammation[J].Respiration Physiology,2001,128:17-22.
  • 6Gorbunov NV,McFaul SJ,Van Albert S.Assessment of inflammatory response and sequestration of blood iron transferrin complexes in a rat model of lung injury resulting from exposure to low-frequency shock waves[J].Crit Care Med,2004,32(4):1028-1034.
  • 7Eichler W,Bechtel JF,Schumacher J,et al.A rise of MMP-2 and MMP-9 in bronchoalveolar lavage fluid is associated with acute lung injury after cardiopulmonary bypass in a swine model[J].Perfusion,2003,18(2):107-113.
  • 8James A.Russell genetic of coagulation factors in acute lung injury[J].Crit Care Med,2003,31(S):S243-S247.
  • 9Johan Groeneveld.Vascular pharmacology of acute lung injury and acute respiratory distress syndrome[J].Vascular Pharmacology,2003,39:247-256.
  • 10Aufmkolk M,Fischer R,Voggenreiter G.Local effect of lung contusion on lung surfactant composition in multiple trauma patients[J].Crit Care Med,1999,27(8):1441-1446.

共引文献58

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部