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血管内皮生长因子和内皮抑素与川崎病的相关性研究 被引量:3

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摘要 川崎病(KO)是一种以免疫系统活化和血管内皮系统广泛损害为特征的全身性血管炎,冠状动脉损伤即是在这种血管炎的基础上发生的.这种血管炎改变是心血管系统病理损伤的重要基础.血管内皮生长因子(VEGF)与内皮抑素(ES)是血管新生的正负调节因子,正常情况下,它们之间保持动态平衡.近年来研究证实,VEGF和ES与成人冠心病的发生关系密切[1],但在川崎病中的研究甚少.本研究旨在探讨VEGF和ES与川崎病发生发展的关系,为川崎病发病机制、治疗的研究提供一定的依据.
出处 《中国药物与临床》 CAS 2012年第6期808-810,共3页 Chinese Remedies & Clinics
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