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脊髓缺血再灌注损伤的研究现状 被引量：9

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摘要 脊髓损伤后恢复血液供应的过程中存在着缺血-再灌注损伤,其机制包括Ca2+超载、自由基损伤、炎症细胞及炎症因子、兴奋性氨基酸、脂质过氧化和细胞凋亡等。现有多种针对发病机制的防止脊髓缺血再灌注损伤(SCIRI)的药物及手段,临床上也多采用综合手段,但效果均不理想。因此,SCIRI的发病机制仍需进一步深入研究。
作者 巩守平
机构地区 西安交通大学医学院第二附属医院神经外科
出处 《西部医学》 2012年第6期1031-1033,共3页 Medical Journal of West China
基金 国家自然科学基金资助项目(30973023) 西安交通大学光华项目之医学创新基金([2010]0203208)
关键词 脊髓缺血再灌注损伤 BOSENTAN 内皮素 血管内皮细胞生长因子
分类号 R744.1 [医药卫生—神经病学与精神病学]
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参考文献18

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二级参考文献26

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共引文献4

同被引文献134

引证文献9

二级引证文献20

西部医学
2012年 第6期

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