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新辅助化疗结合保肢手术治疗骨肉瘤的临床观察 被引量:14

The Clinical Observation of Neoadjuvant Chemotherapy and Limb-salvage Surgery in the Treatment of Osteosarcoma
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摘要 目的探讨新辅助化疗结合保肢手术治疗骨肉瘤的临床疗效。方法对23例四肢骨肉瘤患者实施保肢手术,并分别于术前、术后进行辅助化疗。患者出院后加强随访,并对恢复情况进行功能评定。结果随访期内患者无瘤生存率为69.57%(16/23),术后功能评定优9例、良7例,优良率为69.57%(16/23)。结论新辅助化疗结合保肢手术治疗骨肉瘤患者疗效较好,值得临床推广应用。 Objective To study the effect of neoadjuvant chemotherapy and limb-salvage surgery in the treatment of osteosarcoma. Methods Twenty three patients with osteosarcoma were treated by neoadjuvant chemotherapy and limb-salvage surgery, all the patients were follow-up and the function of the ill limb were also assessed. Results The free tumor survival rate of patients in the follow-up period was 69.57% (16/23) ; the 9 patients were in the first grade, the 7 patients were in the second grade, the proportion of the patients possessed better function was 69.57% (16/23). Conclusion Neoadjuvant chemotherapy and limb-salvage surgery is effect in the treatment of osteosarcoma.
作者 龚印华
出处 《肿瘤基础与临床》 2012年第3期221-223,共3页 journal of basic and clinical oncology
关键词 骨肉瘤 新辅助化疗 保肢手术 osteosarcoma neoadjuvant chemotherapy limb-salvage surgery
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