辨证治疗胃食管反流病的临床疗效观察

Clinical Effects of Treatment Based on Syndrome Differentiation for Gastroesophageal Reflux Disease

目的:评价胃食管反流病中医辨证论治的临床疗效。方法:将216例胃食管反流病患者以2∶1比例随机分为中药组144例和西药组72例。中药组给予中医辨证治疗,西药组给予奥美拉唑治疗,疗程均为8周。评价两组患者的临床疗效及内镜下食管黏膜炎症改善疗效。结果:中药组和西药组的临床疗效总有效率分别为94.20%和72.46%,两组比较差异具有统计学意义(P<0.01);中药组和西药组胃镜下食管黏膜炎症改善疗效的总有效率分别为51.14%和50.00%,两组比较差异无统计学意义(P>0.05)。结论:中医辨证论治胃食管反流病具有较好的疗效,可有效缓解患者的症状,在改善内镜下食管黏膜炎症方面亦具有一定的作用。

Objective： To evaluate the therapeutic effects of treatment based on syndrome differentiation fi）r gastruesophageal reflux disease （GERD）. Methods： Two bundled and sixteen patients with GERD were randomly divided into Chinese medicine group （n = 144） and western medicine group （n =72） according to 2：1 ratio, The Chinese medicine group was treated by syn drome differentiation therapy and the western medicine group was treated by omeprazole, with the coupe of eight weeks. The clini- cal and endoscopic etfects of two groups were evaluated. Results： The total clinical effective rates of Chinese medicine group and western medicine group were 94, 20% and 72.46% respectively, with a statistical difference between the two groups （P 〈 0.01 ）, The total endoscopic effective rates of Chinese medicine group and western medicine group were 5 1. 14% and 50.00% respectively, without statistical difference between the two groups （P 〉0.05）. Conclusion： The treatment based on syndrome differentiation has good effects on GERD, and can improve the clinical symptoms and the esophageal nmcosal inflammation effectively.