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伊立替康联合顺铂治疗晚期食管癌40例临床疗效观察 被引量:5

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摘要 目的:探讨伊立替康联合顺铂治疗晚期食管癌的临床效果。方法:选择我院晚期食管癌患者80例,将以上患者随机分为观察组和对照组。观察组给予伊立替康和顺铂。对照组给予顺铂和5-氟尿嘧啶。结果:观察组缓解率和控制率分别与对照组比较,差异有统计学意义(P<0.05);两组1年生存率比较,差异有统计学意义(P<0.05);观察组骨髓抑制、腹泻发生率显著高于对照组,差异有统计学意义(P<0.05)。结论:伊立替康联合顺铂能显著提高晚期食管癌治疗效果,虽然增加了骨髓抑制和腹泻的发生率,但患者能够耐受。
出处 《北方药学》 2012年第6期64-64,共1页 Journal of North Pharmacy
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