双膦配体修饰铑催化乙酸乙烯酯氢甲酰化反应(英文)

Regioselective Rhodium-Diphosphine Ligand Catalyzed Hydroformylation of Vinyl Acetate

研究了双膦配体对铑催化的乙酸乙烯酯氢甲酰化反应的促进作用,结果表明,在优化反应条件下,以双膦化合物2,2’-二(二苯膦甲基)-1,1’-联苯(BISBI)为配体时,铑催化乙酸乙烯酯氢甲酰化反应的TOF(转化频率)值达到4000h1,生成2-乙酰氧基丙醛的选择性>99%.当在较温和的条件下Rh/BISBI催化乙酸乙烯酯氢甲酰化反应较长时间时TON(转化数)值达到9200,成醛率超过90%,2-乙酰氧基丙醛选择性仍保持>99%.

Rhodium-catalyzed hydroformylation of vinyl acetate with the use of diphosphine ligands was studied.A high regioselectivity（branched：linear of 99：1） and activity（TOF：4000 h-1） under optimum conditions were achieved by using a 2,2’-bis（diphenylphosphino methyl）-1,1’-biphenyl ligand.The high turnover number（9200） obtained under mild conditions and stability of the catalyst indicates that it would be useful for industrial vinyl acetate hydroformylation.