四种羌活抗心律失常作用比较

A Comparison of Anti-arrhythmic Effects of Four Kinds of Rhizoma Seu Radix Nomopterygii

本实验比较了四种羌活(简称Ni.Nf.Pr.As)抗心律失常作用,实验发现四种羌活均能缩短乌头碱诱发的心律失常持续时间以及延长其潜伏期。Ni能延长CaCl_2诱发的室颤发生时间,Pr能延长BaCl_2诱发的心室停搏时间。鉴于羌活尚具有镇静作用,羌活可望作为良好的抗心律失常药。

Experiments were conducted to compare the anti-arrhythmic effects of the four kinds of Qianghuo( Notopterygium incisum; N. forbesii; Pleurospermum rivulorum; Angelica silvestris). It has been found that all the four kinds of Qianghuo can antagonize arrhythmia induced by aconitine. Notopterygium incisum can prolong the ventricular vibration induced by CaCl_2 and Pleurospermum rivulorum can prolong the ventricle stop induced by BaCl_2. Thus Qianghuo can be used as a sedative and anti-arrhythmic drug.