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膀胱肿瘤实验研究现状及展望 被引量：2

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摘要 膀胱肿瘤是最常见的恶性肿瘤之一，近年来发病率持续升高，目前居所有恶性肿瘤的第9位，而在我国其发病率居泌尿系统恶性肿瘤第1位。绝大多数膀胱上皮肿瘤（UCC）来源于移行上皮肿瘤（TCCs），生物学行为复杂多变，如治疗后易复发、浸润转移及对化疗药物抵抗等。因此，
作者 胡嘏 叶章群
机构地区 华中科技大学同济医学院附属同济医院泌尿外科
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2012年第6期997-999,共3页 Chinese Journal of Experimental Surgery
关键词 膀胱肿瘤 实验研究 泌尿系统恶性肿瘤 移行上皮肿瘤 膀胱上皮肿瘤 生物学行为 药物抵抗 浸润转移
分类号 R737.14 [医药卫生—肿瘤]
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参考文献40

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同被引文献13

  • 1Yan P,Fu J,Qu Z,et al.PDLIM2 suppresses HTLV-I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation[J].Blood,2009,113 (18):4370-4380.
  • 2Qu Z,Yan P,Fu J,et al.DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target[J].Cancer Res,2010,70 (5):1766-1772.
  • 3Qu Z,Fu J,Yan P,et al.Epigenetic repression of PDZ-LIM domaincontaining protein 2:implications for the biology and treatment of breast cancer[J].J Biol Chem,2010,285 (16):11786-11792.
  • 4Yu HG,Yu LL,Yang Y,et al.Increased expression of RelA/nuclear factor-κB protein correlates with colorectal tumorigenesis[J].Oncology,2003,65(1):37-45.
  • 5Saccani S,Marazzi I,Beg AA,et al.Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response[J].J Exp Med,2004,200(1):107-113.
  • 6Tanaka T,Grusby M J,Kaisho T.PDLIM2-mediated termination of transcription factor NF-κB activation by intranuclear sequestration and degradation of the p65 subunit[J].Nat Immunol,2007,8 (6):584-591.
  • 7Vanoirbeek E,Eelen G,Verlinden L,et al.PDLIM2 expression is driven by vitamin D and is involved in the pro-adhesion,and anti-migration and-invasion activity of vitamin D[J].Oncogene,2014,33(15):1904-1911.
  • 8Yah P,Qu Z,Ishikawa C,et al.Human T-cell leukemia virus type Ⅰ-mediated repression of PDZ-LIM domain-containing protein 2 involves DNA methylation but independent of the viral oncoprotein tax[J].Neoplasia,2009,11 (10):1036-1041.
  • 9张思维,马建辉,李鸣,那彦群,陈万青.中国部分市县膀胱癌发病趋势比较研究[J].中华泌尿外科杂志,2009,30(10):673-676. 被引量：42
  • 10黎玮,齐进春.膀胱肿瘤诊断的实验研究进展与展望[J].中华实验外科杂志,2010,27(3):279-281. 被引量：9

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中华实验外科杂志
2012年 第6期

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