关于抑郁症辨证分型及用药规律的第一轮专家问卷分析

First round of expert questionnaire on syndrome types and medication laws of depression

目的从专家经验角度探索抑郁症常见中医证候类型及药物。方法根据文献资料及前期抑郁症患者中医证候调查结果,利用德尔菲法编制抑郁症常见中医诊治专家问卷,向全国范围内遴选出的75位专家发放调查问卷,对所得数据进行积极度、集中程度、协调程度、权威程度的统计与评价。结果第一轮问卷回收率93.20%;9个抑郁症证型中,重要性较高的条目为6项,占调查指标的66.67%;12个抑郁症常用方剂中,重要性较高的条目共7项,占总条目的 58.30%;变异系数小于0.25的证型为8项,常用方剂为6项,常用药物为9项;专家权威程度平均值为0.82。结论肝郁气滞证、肝郁痰阻证、肝郁脾虚证、肝郁化火证为抑郁症的常见中医证候;逍遥散、柴胡疏肝散、温胆汤、柴胡加龙牡汤、四逆散、血府逐瘀汤为治疗抑郁症的常用方剂。

Object To investigate experts＇ experience. Methods the syndrome types of depression and used medicinal from the angle of The expert questionnaire was established by using Delphi method according to literature and results of previous survey on TCM syndrome types in the patients with depression. The questionnaire was given out to 75 experts selected from the whole country. The positive degree, concentrative degree, coordination degree and authority degree of obtained data were counted and reviewed. Results The reclamation rate of the first round questionnaire was 93. 20%. Among 9 syndrome types of depression, there were 6 items （66.67%） with higher importance. Among 12 common formulas for treating depression, there were 7 items （58.30%） with higher importance. There were 8 syndrome types with variation coefficient being less than 0. 25, 6 common formulas and 9 common medicinal. The average value of authority degree was 0.82. Conclusion The common syndrome types of depression include syndrome of liver depression and qi stagnation, syndrome of liver depression and phlegm obstruction, syndrome of liver depression and spleen deficiency, and syndrome of depressed liver qi transforming into fire. The common formulas for treating depression include Xiaoyao San, Chaihu Shugan San, Wendan Tang, Chaihu and Lumu Tang, Sini San and Xuefu Zhuyu Tang.