血清尿酸C-反应蛋白在急性心肌梗死中的诊断价值

Diagnostic value of serum uric acid, C-reactive protein in acute myocardial infarction

目的探讨血尿酸（uricacid，UA）、C-反应蛋白（C—reactiveprotein，CRP）在诊断急性心肌梗死中的意义。方法对100例急性心肌梗死患者及100例对照组进行UA、CRP等生化指标检测，检测患者入院后第1、3、7天的血清uA、CRP，而对照组仅做1次测量。结果急性心肌梗死患者血糖、甘油三酯、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）、UA、CRP水平明显增高，差异有统计学意义（P〈0．05）；在7d的检测中CRP有显著变化（P〈0．05），UA差异无统计学意义（P〉0．05）。结论UA、CRP、高血压、高血糖、高甘油三酯、高LDL和低HDL与急性心肌梗死的发生有关，可以将它们作为急性心肌梗死诊断的参考指标。血清CRP在7d的变化尤为重要。

Objective To investigate the significance of serum uric acid （UA） and C-reactive protein （CRP） in diagnosis of acute myocardial infarction （AMI）. Methods The serum levels of UA, CRP and other biochemical indicators were measured in 100 cases of acute myocardial infarction （AMI） and 100 cases in control group. The serum levels of UA and CRP were detected at the first, 3th and 7th day after admission of patients with AMI, whereas only one time measurement was performed in control group. Results In patients with acute myocardial infarction, the serum evels of UA, CRP, BS, TG, LDL, HDL were significantly higher than those in control group （P 〈 0. 05 ） ;In serial measurements, the levels of CRP showed significant alterations during 7 days （P 〈 0. 05）, the alterations in levels of UA were not statistically significant （P 〈 0.05）. Conclusions The levels of UA, CRP, hypertension, hy- perglycosemia, high TG, high LDL and low HDL are correlated with AMI, and can be used for reference indexes in diagnosis. The changes of serum CRP has more important significance within 7 days.