钙化上皮瘤的病理特征分析

Clinical and pathological features of calcifying

目的探讨钙化上皮瘤的临床特点及病理特征，提高对钙化上皮瘤的鉴别诊断水平。方法回顾性分析解放军150中心医院病理科2005年至2011年期间36例诊断为钙化上皮瘤患者的临床资料及病理资料。结果88．89％（32／36）钙化上皮瘤患者年龄〈29岁，病变全部位于头颈部及上臂；77．78％（28／36例）的患者临床误诊为其他疾病，手术切除后均无复发，组织病理观察，其镜下表现为典型的嗜碱性细胞及影细胞排列为主。结论钙化上皮瘤好发于青少年，其临床误诊率较高，手术彻底切除可预防复发，此病变具有多样化的临床表现，对颈部、上臂、头面部皮肤单个结节，应考虑钙化上皮瘤的可能。

Objective To study the clinical and pathological features of calcifying epithelioma, and improve the defferential diagnosis level of the disease. Methods The clinical and pathological data of 36 cases of calcifying epithelioma confimed with pathology in the pathology department after surgical re- section from January 2005 to December 2011 were retrospectively analyzed. Results The diseased re- gion were upper arm, head and neck： 88.89% （32/36） calcification of epithelial tumors were younger than 29 years, 77.78% （28/36）were misdiagnosed as others diseases, and without recurrence after sur- gical resection. The basophilic and shadow cells were arranged mainly in tissue. Conclusions Calcif- ying epithelioma occures mainly in upper arm, head and neck of young people. It has higher rate of clini- cal misdiagnosis, without recurrence after surgical resection, and a variety of clinical manifestations, which may contribute to its diagnosis.