86株肠球菌所致医院感染与耐药性研究分析

86 enterococci of nosocomial infection and drug resistance analysis

目的研究分析肠球菌所致医院感染由于耐药性。方法针对2009年11月至2011年11月分离出的86株肠球菌(来自2458份标本)进行研究,试验中使用细菌鉴定仪和K-B法给予鉴定和检测。结果 86株肠球菌中多数为粪肠球菌,占总菌数的60.5%(52株),其次为屎肠球菌,占总菌数的31.4%(27株),剩余8.1%(7株)为其他。相对于屎肠球菌,粪肠球菌对常用抗生素环丙沙星等耐药率更低;相对于粪肠球菌,屎肠球菌对氨基糖苷类抗生素耐药率更低。红霉素的耐药率均较高,万古霉素的耐药率均较低。结论药物选择应遵循合理用药原则,参考药敏试验结果,制定相关预防措施。

Objective To study analysis of enterococci of nosocomial infections due to drug resistance. Methods 86 enterococci isolated for November 2009 November to 2011 （from 2458 samples） to conduct re- search, given to the identification and detection of bacterial identification instrument used in the experiments and the KB method. Results The majority of the 86 Enterocoeeus Enterococcus faecalis and total bacteria count of 60. 5% （52）, followed by 31.4% of Enterocoecus faecium, the number of total bacteria （27）, and the remaining 8. 1% （7） for the other. Enterococcus faecium, Enterococcus faecalis commonly used antibiotic ciprofloxacin, resistance rates lower ; and compared to Enterococcus faecalis, Enterocoecus faecium aminoglyco- side resistance rates lower. Erythromyein resistance rate wer~ higher, the vaneomyein resistance rate was lower. Conclusion The drug of choice should follow the principles of rational drug reference drug susceptibility test results to develop preventive measures.