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70岁以上老年非小细胞肺癌患者的综合预后分析 被引量:6

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摘要 目的探讨影响70岁以上老年非小细胞肺癌(NSCLC)患者预后生存的因素。方法回顾性分析2005年1月至2006年12月收治的361例70岁以上老年NSCLC患者的临床资料,随访生存情况,分析年龄、性别、吸烟状况、Karnofsky评分(KPS)、TNM分期、病理类型、治疗方式、合并症情况(Charlson合并症指数CCI)等因素,对老年非小细胞肺癌患者生存期的影响。结果全组患者平均年龄(73.4±3.1)岁(70~86岁),确诊肺癌后中位生存期34.0个月(0.3~83.0个月),5年生存率34.1%。对年龄、性别、病理类型、是否吸烟、KPS、TNM分期、治疗方式、是否伴有合并症等预后因素进行单因素分析,结果显示:TNM分期、治疗方式、KPS、是否伴有合并症与预后相关。Cox多因素分析显示TNM分期、有无合并症、治疗方式是影响患者生存及预后的独立因素。结论 TNM分期、治疗方式、合并症等多种因素影响70岁以上老年NSCLC患者的预后生存。老年肺癌患者多伴有合并症,重视并积极控制合并症,有助于改善预后,延长生存。
出处 《中国医刊》 CAS 2012年第6期49-51,共3页 Chinese Journal of Medicine
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