树突状细胞的提取与肿瘤免疫治疗之间的关系

The Relationship between the Extraction of Dendritic Cells and the Immunotherapy of Tumor

人类树突状细胞(DC)是连接先天性免疫反应和获得性免疫反应的桥梁。做为一种抗原提呈细胞(APC),DC可以提呈肿瘤抗原并激活抗肿瘤的免疫反应。许多的研究和临床试验都证实了DC在肿瘤治疗上面的巨大潜能。不断提高对DC的认识,有助于改进和提高其临床应用的方法。

Dendritic cells form the connection between innate and adoptive mechanisms of the immune system.As antigen-presenting cells,dendritic cells are capable of presenting tumour antigen and effectively stimulating immune response targeted against tumour.A number of preclinical and clinical studies document dendritic cells′ potential in anti-cancer treatment.Increasing knowledge of dendritic cell biology is leading to improved methods for their preparation for clinical application.