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Histopathological studies and oxidative stress of synthesized silver nanoparticles in Mozambique tilapia (Oreochromis mossambicus) 被引量:14

Histopathological studies and oxidative stress of synthesized silver nanoparticles in Mozambique tilapia (Oreochromis mossambicus)
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摘要 To evaluate the potential environmental effects of engineered nano metals,it is important to determine the adverse effects of various nanomaterials on aquatic species.Adult tilapia (Oreochromis mossambicus) were maintained in 10 L glass aquaria,and exposed to a graded series of synthesized silver nanoparticles (Ag-NPs) at 25,50 and 75 mg/L for eight days.The LC 50 value was 12.6 mg/L.Reduced activities of antioxidant enzymes and the contents of antioxidants were lowered in the gills and liver of fishes treated with AgNPs,which resulted in heavy accumulation of free radicals.Histopathological results imply that the balance between the oxidative and antioxidant system in the fish was broken down during Ag-NPs exposure.The principal concern related with the release of nanomaterials and their smaller particle may change the materials transport and potential toxicity to aquatic organisms compared to larger particles. To evaluate the potential environmental effects of engineered nano metals,it is important to determine the adverse effects of various nanomaterials on aquatic species.Adult tilapia (Oreochromis mossambicus) were maintained in 10 L glass aquaria,and exposed to a graded series of synthesized silver nanoparticles (Ag-NPs) at 25,50 and 75 mg/L for eight days.The LC 50 value was 12.6 mg/L.Reduced activities of antioxidant enzymes and the contents of antioxidants were lowered in the gills and liver of fishes treated with AgNPs,which resulted in heavy accumulation of free radicals.Histopathological results imply that the balance between the oxidative and antioxidant system in the fish was broken down during Ag-NPs exposure.The principal concern related with the release of nanomaterials and their smaller particle may change the materials transport and potential toxicity to aquatic organisms compared to larger particles.
出处 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2012年第6期1091-1098,共8页 环境科学学报(英文版)
关键词 silver nanoparticles Oreochromis mossambicus oxidative stress analysis histopathological studies toxic effect silver nanoparticles Oreochromis mossambicus oxidative stress analysis histopathological studies toxic effect
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