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黄柏提取物在体外对Vero细胞单纯疱疹病毒1型的抑制作用 被引量:2

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摘要 目的:观察黄柏提取物在体外对单纯疱疹病毒1型的抑制作用。方法:以HSV-1型病毒感染Vero细胞,检测黄柏提取物对单纯疱疹病毒1型(HSV-1)引起的细胞病变的抑制作用,并用阿昔洛韦作对照。结果:黄柏提取物抗病毒的作用优于西药阿昔洛韦组(P<0.05)。结论:黄柏提取物浓度范围0.31~10mg/ml,对10-2和10-5稀释度HSV-1(Sm44株)所致的Vero细胞病变有剂量依赖性抑制作用,IC50值分别为4.19和1.12mg/ml。
作者 李涛 彭立新
出处 《中国社区医师(医学专业)》 2012年第16期5-6,共2页
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