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通心络联合氯吡格雷在非心源性脑梗死二级预防中的作用 被引量:1

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摘要 目的:探讨通心络联合氯吡咯雷对非心源性脑梗死二级预防的效果。方法:97例急性脑梗死患者随机分为2组,对照组48例给予氯吡咯雷治疗,治疗组49例加用脑心通胶囊,疗程均为6个月,比较2组治疗前后血浆D-二聚体(D-D)、超敏C-反应蛋白(hs-CRP)水平、颈动脉内-中膜厚度(IMT)。结果:2组治疗前后各指标间差异均有显著性意义(P<0.05),治疗组改善更为明显,治疗后2组各指标间差异均有显著性(P<0.05)。结论:通心络联合氯吡咯雷治疗对于非心源性脑梗死的二级预防疗效显著,且安全可靠,为脑梗死的治疗提供了选择的机会。
出处 《中医药临床杂志》 2012年第6期493-494,共2页 Clinical Journal of Traditional Chinese Medicine
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参考文献8

  • 1王力,张茁.缺血性脑卒中二级预防的循证医学证据[J].中华老年心脑血管病杂志,2007,9(8):574-576. 被引量:36
  • 2王连芹 宁海春 于强 等.脑梗死再发危险因素研究.河北医科大学学报,2009,30(11):1168-1170.
  • 3LowegD,Yarnell JW,Rumley A et a1.C-reactive protein’fibrin D-di-mer,and incident ischemic heart disease in the Speedwell study:are in-flammation and fibrin turnover linked in the pathogenesis.Arterioscler thromb Vasc Biol,2001,2l:603-610.
  • 4Robson SC,Shephard EG,Kir-sch RE.Fibrin degradation product D-dimer induces the synthesis and release of biologically active IL-l beta,IL-6 and plasminogen activator inhibitors from monocytes in vitro.Br J haematol,1994,86(2):322.
  • 5Mauriello A,Sangiorgig,Palmierig,et al.Hyperfibrinogenemia is associ-ated with specific histocytological composition and complications of ath-erosclerotic carotida plaques affected by transient ischemic attack.Cir-culation,2000,10l(7):744-750.
  • 6Koenig W.Fibrinogen in cardiovascular disease:an update.Thromb Haemost.2003,89(4):601-609.
  • 7梅运涛.通心络胶囊对急性脑梗死患者全血粘度及纤维蛋白原变化的影响[J].河南实用神经疾病杂志,2003,6(6):61-61. 被引量:18
  • 8LowegD.The relationship between infection,inflammation,and cardio-vascular disease:an overview.Ann Periodontol,2001,6(1):1-8.

二级参考文献15

  • 1王伊龙.临床应用重组组织型纤溶酶原激活剂静脉溶栓治疗缺血性卒中专家共识[J].中华内科杂志,2006,45(7):613-614. 被引量:52
  • 2各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33020
  • 3孟家眉.对脑卒中临床研究工作的建议[J].中华神经精神科杂志,1988,21:57-58.
  • 4王柏生 汪丽娟.临床血液流变学[M].郑州:河南科学技术出版社,1994.32.
  • 5Bhatt DL,Fox KA,Hacke W,et al.CHARISMA Investigators.Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events[J].N Engl J Med,2006,354:1706-1717.
  • 6Diener HC,Bogousslavsky J,Brass LM,et al.MATCH investigators.Aspirin and clopidogrel compared with clopidogrel alone after recent ischemic stroke or transient ischemic attack in high-risk patients (MATCH):randomized,doubleblind,placebo-controlled trial[J].Lancet,2004,364:331-337.
  • 7Sandercock P,Mielke O,Liu M,et al.Anticoagulants for preventing recurrence following presumed non-cardioembolic ischemic stroke or transient ischemic attack (Cochrane Review)[A].In:The Cochrane Database of Systematic Reviews.2002:CD000248.
  • 8Gubitz G,Sandercock P,Counsell C.Anticoagulants for acute ischemic stroke (Cochrane Review)[A].In:The Cochrane Database of Systematic Reviews[M].2004:CD000024.
  • 9Saxena R,Koudstaal PJ.Anticoagulants for preventing stroke in patients with non rheumatic atrial fibrillation and a history of stroke or transient ischemic attack (Cochrane Review)[A].In:The Cochrane Database of Systematic Reviews[M].2004:CD000185.
  • 10PROGRESS Collaborative Group.Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischemic attack[J].Lancet,2001,29,358:1033-1041.

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