微创经皮肾镜下钬激光治疗泌尿系统结石的临床疗效分析

Efficacy of Minimaily Invasive Percutaneous Nephrolithotomy in the treatment of upper urinary calculi

目的探讨微创经皮肾镜下钬激光(MPCNL)治疗泌尿系上尿路结石的临床疗效和安全性。方法本院收治120例泌尿系统上尿路结石患者,66例患者接受MPCNL治疗,54例患者接受输尿管镜取石术(URL)治疗,比较两组患者术后疗效。结果 MPCNL组与URL组患者手术成功率分别为100.0%和61.1%,一次结石清除率分别为90.9%和55.6%,术后1个月结石清除率分别为100.0%和83.3%,上述指标MPCNL组均显著优于URL组,差异具有统计学意义(P<0.05)。结论微创经皮肾镜钬激光碎石术治疗上尿路结石成功率和结石清除率高,并发症发生率低,值得临床推广。

Objective To discuss the efficacy and safety of Minimally Invasive Percutaneous Nephrolithotomy （MPCNL） in treatment of upper urinary calculi of urinary system. Methods The 120 cases of upper urinary calculi in our hospital were divided into MPCNL treatment group and URL treatment group. 66 patients received MPCNL treatment, 54 patients re- ceived URL treatment. Their clinical data were respectively analyzed. Results Compared with the URL group, the MPCNL group got a higher success rates （100.0% vs 61.1%, P 〈 0.05） and stone free rates both at one day and one month after oper- ation （90.9% vs 55.6%, P 〈 0.05; 100% vs 83.3%, P 〈 0.05）. Conclusion High success rate and stone free rate can be obtained with MPCNL for urinary calculi of urinary system. At the same time, the treatment of MPCNL has low complications rate.