硫糖铝联合法莫替丁治疗急性胃炎疗效观察

The clinical efficacy of Sucralfate combined with Famotidine in treatment of acute gastritis

目的观察硫糖铝联合法莫替丁治疗急性胃炎的临床疗效。方法选择2007年3月～2012年1月于本院消化内科、内科就诊并被诊断为急性胃炎的患者217例,严格按照随机化的原则将所有入选患者按奇数、偶数分为对照组109例和治疗组108例,对照组采用法莫替丁40mg静脉输注,治疗组在采用法莫替丁治疗的同时外加硫糖铝,治疗后两组进行疗效对比。结果 1个疗程后,治疗组的有效率为95.6%,对照组的有效率为86.2%,两组的疗效差异具有统计学意义(P<0.05)。结论硫糖铝联合法莫替丁治疗急性胃炎比单用法莫替丁能够取得更好的临床疗效,值得进一步推广使用。

Objective To observe the clinical efficacy of Sucralfate combined with Famotidine in treatment of acute gastri- tis. Methods To choose 217 cases of patients diagnosed with acute gastritis between March 2007 and January 2012 in our hospital, all enrolled patients were divided into two groups in strict accordance with the principles of randomization, the treatment group had 109 cases, and the control group had 108 cases. The control group was given Famotidine 40 mg intra- venous infusion while the treatment group added Sucralfate on basis of Famotidine. Results After a course of treatment, the treatment group＇s effective rate was 95.6% and that of control group was 86.2%, the differences of the two groups was sta- tistically significant （P 〈 0.05）. Conclusion The clinical efficacy of Sucralfate combined with Famotidine in treatment of a- cute gastritis is better than the single use of Famotidine, it is worthy of promotion.