腹膜转运特性对持续性不卧床腹膜透析患者营养状况的影响

The influence of peritoneal transport characteristics on the nutritional status of patients with continuous ambulatory peritoneal dialysis

目的了解持续性不卧床腹膜透析（CAPD）患者腹膜转运特性对营养状况的影响。方法对73例CAPD患者进行横断面研究，根据腹膜平衡试验（PET）结果分为高转运组43例与低转运组30例，根据主观综合性营养评估法（SGA）评分对患者营养状况进行评估，同时对两组白蛋白（ALB）、总蛋白（TP）、血红蛋白（Hb）、原发病、年龄、体重、透析时间、超滤量、血尿素氮（BUN）、血肌酐（SCr）等进行比较。结果两组患者年龄、体重、超滤量、收缩压、舒张压、Hb、SGA评分、BUN、SCr比较差异无统计学意义（P〉0．05）；高转运组透析时间（14．35±13．88）个月，原发病为糖尿病肾病（DN）16例、非DN27例，TP（64．98±7．59）g／L，ALB（34．61±5．43）g／L，与低转运组的（24．20±19．62）个月、12例和18例、（68．73±6．96）g/L、（38．71±3．82）g/L比较差异有统计学意义（P〈0．05）。结论不同腹膜转运特性CAPD患者营养状况存在明显差异，CAPD高转运患者营养状况较差。

Objective To explore the influence of peritoneal transport characteristics on the nutritional status of patients with continuous ambulatory peritoneal dialysis（CAPD）. Methods Seventy-three CAPD patients were involved in this cross-sectional study. According to the results of peritoneal equilibration test（PET）, the patients were divided into high transport group with 43 cases and low transport group with 30 cases. Nutritional status was evaluated with the subjective global assessment （SGA） score and the differences were analyzed between two groups in the albumin （ALB）,total protein （TP）,hemoglobin （Hb）,primary disease, age, weight, dialysis time, ultrafiltration, blood urea nitrogen （BUN）, serum creatinine （SCr） and so on. Results There was no difference between two groups in age,weight,ultrafiltration, systolic blood pressure, diastolic blood pressure, Hb, SGA score, BUN and SCr （P 〉 0.05 ）. However, the dialysis time, the case number of diabetic nephrepathy （DN） as original disease,the case number of non DN as original disease,TP and ALB between high transport group and low transport group had significant differences [（14.35 ± 13.88） months vs. （24.20 ± 19.62） months,16 cases vs. 12 cases,27 cases vs. 18 cases, （64.98 ± 7.59） g/L vs.（68.73 ± 6.96） g/L, （34.61 ± 5.43） g/L vs. （38.71 ± 3.82） g/L,P〈 0.05 ]. Conclusions The nutritional status of CAPD patients with different transport characteristics have significant differences. CAPD patients with high transport characteristics are complicated with worse nutritional status,compared with those patients with low transport characteristics.