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厄贝沙坦对高血压左心室肥厚的逆转及心功能影响的研究 被引量:2

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摘要 探讨厄贝沙坦的降压效果,以及对高血压左心室肥厚的逆转和心功能影响。方法原发性高血压并左心室肥厚患者65例口服厄贝沙坦疗程20周,观察血压心率,多普勒超声心动图检测左心室厚度及心功能。结果治疗后收缩压与舒张压均有明显下降(P<0.01),而心率无明显下降(P>0.05):治疗后舒张期左室后壁厚度、舒张期室间隔厚度、左室质量指数均有显著下降(P<0.01):治疗后心排血量、舒张早期峰值流速/舒张晚期峰值流速、左室射血分数较治疗前有明显改善(P<0.01)。结论厄贝沙坦有良好的降压效应,而且能够逆转左心室肥厚,改善心功能,可以作高血压合并左心室肥厚患者首选治疗。
作者 曾元杰
出处 《中国实用医药》 2012年第13期149-150,共2页 China Practical Medicine
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参考文献5

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