子宫颈刮片中鳞状化生细胞的形态特征及临床意义

Morphologic Characteristics of Squamous Metaplastic Cells in Smear of Crevix and Their Clinical Implications

从1000例宫颈涂片中发现鳞状化生细胞191例(19.1％)。但化生型重度核异质细胞只有2例(1.05％)。化生细胞病例的76.44％均有子宫颈炎症性改变。放射治疗后1～6月随诊病例中35％发现化生细胞。本文指出,化生细胞在30～40岁年龄组出现率最高,化生与子宫颈局部炎症有密切关系,放疗对化生作用有影响。提出储备细胞增生应与低分化鳞癌细胞和未分化癌细胞相鉴別;未成熟化生细胞易与外底层细胞混淆;切勿将成熟化生细胞误为鳞癌细胞。

Out of 1,000 cases which had smears made from the uterine cervix, there were 191 patients in whom squamous metaplastic cells (19.1%) were found. Of the latter 2 had marked atypical metaplastic cells (1.05%). In those who had squamous metaplastic cells in the smear 76.44% showed chronic inflammation of the cervix. In patients who were 1-6 months after radiotherapy, metaplastic cells were found in 35% of cases. It is emphasized that it is important to differentiate proliferation of reserve cell from lowly and undifferentiated carcinoma cell, and that immature metaplastic cell is readily confused with parabasal layer cells, and care should be taken not to mistake mature metaplastic cells for squamous carcinomatous cell.