摘要
目的探讨0.2%酒石酸溴莫尼定滴眼液对近视患者屈光手术后夜间视觉质量的影响。方法 2010年12月到2011年6月在我院接受屈光手术的近视患者31例(62只眼)。通过问卷调查应用0.2%酒石酸溴莫尼定滴眼液前及应用0.2%酒石酸溴莫尼定滴眼液1个月后的夜间视觉质量的变化。应用波前像差仪观察屈光手术后1个月时,充分暗适应后、应用0.2%酒石酸溴莫尼定滴眼液前的患者瞳孔直径及高阶像,并测定同一患者在应用0.2%酒石酸溴莫尼定滴眼液30 min后的瞳孔直径及高阶像。结果在应用0.2%酒石酸溴莫尼定1个月后,所有患者主觉夜间视觉质量都有不同程度的提高。应用0.2%酒石酸溴莫尼定滴眼液之前,瞳孔的平均直径为(7.50±1.09)mm,高阶像差值为(53.65±20.92)%;应用0.2%酒石酸溴莫尼定30 min后瞳孔的直径为(6.85±1.02)mm,高阶像差值为(46.62±17.57)%。在应用0.2%酒石酸溴莫尼定后30 min后,所有的患者瞳孔直径及高阶像差都有很明显的变化,差异具有显著性。结论屈光手术后应用0.2%酒石酸溴莫尼定滴眼液可以缩小瞳孔,降低高阶像差,改善夜间视觉质量。
Objective To evaluate the efficacy of brimonidine tartrate ophthalmic solution 0.2% in patients about night-vision quality after laser refractive surgery.Methods 31 patients(62 eyes) who accepted refractive surgery in our hospital from December 2010 to June 2011 were reviewed.A quality-of-vision questionnaire was given at the enrollment in the study and repeated 1 month after treatment.WaveScan Wavefront was applied to determine pupil diameter and higher order aberration one month after refractive surgery.Testing was performed before brimonidine tartrate ophthalmic solution 0.2% administered to whom had already fully dark adaptation.Measurements were repeated 30 minutes after the use of brimonidine tartrate 0.2% solution.Results Patients received a questionnaire at enrollment and at the 1-month follow-up to assess visual improvement.The mean pupil diameter before administration of brimonidine tartrate ophthalmics o.2% was(7.50±1.09)mm and the mean higher order aberration was(53.65±20.92)%.Pupil diameter 30 minutes after instillation had decreased to(6.85±1.02)mm and higher order aberration had decreased to(46.62±17.5).30 minutes after using brimonidine tartrate 0.2% solution,patients had significant change in Pupil diameter and higher order aberration.Conclusion Brimonidine tartrate ophthalmic solution 0.2% can narrow pupil,reduce higher order aberration and improve night-vision quality.
出处
《临床眼科杂志》
2012年第3期229-231,共3页
Journal of Clinical Ophthalmology
关键词
酒石酸溴莫尼定滴眼液
屈光手术
夜间视觉质量
Brimonidine tartrate ophthalmic solution
Refractive surgery
Night-vision quality