血脂、血压对早期糖尿病视网膜病变进展的影响

Analysis of risk factors of early diabetic retinopathy

目的探讨血脂、血压对早期糖尿病视网膜病变(DR)进展的影响。方法收集DR-0期,轻、中、重度非增生性糖尿病视网膜病变(NPDR)各20例,对照组30例,记录血脂、血压在不同分组中的测量值,分析其与早期DR发生发展的关系。结果 DR组的收缩压(SBP)、胆固醇(CHO)、甘油三酯(TG)明显高于正常对照组,而高密度脂蛋白(HDL)则低于对照组;且TG与DR的病变程度呈显著正相关。结论 CHO、TG是DR的危险因素,HDL是DR的保护因素,且TG可能与DR的发展有相关性。

Objective To study the influences of related systemic factors for diabetic retinopathy（DR）.Methods The early DR were divided into four periods which include DR-0 period,mild,moderate and severe degree of non-proliferative diabetic retinopathy（NPDR）.An examination outcomes from 30 cases of each DR group and 40 cases of normal control group including age,level of blood glucose,systolic blood pressure,diastolic blood pressure and serum lipid level were recorded.Analysis of its relationship with the progression of early diabetic retinopathy.Results SBP、CHO、TG and LDL of DR Group was enhenced in comparison with the normal control group（P 0.05）;while HDL is lower than the control group（P0.05）.TG and the process degree of DR demonstrate a significant positive correlation（P0.01）.Conclusion SBP、 CHO、TG and LDL are major risk factors for the occurence of DR,TG may be related to the development of DR.It is extremely important to control the related risk factors in the occurrence and development of DR.