健康青年人经眼前庭诱发肌源性电位检查

Study of ocular-vestibular evoked myogenic potentials in healthy people

目的评价经眼外肌引出的前庭诱发肌源性电位的临床应用价值。明确潜伏期、振幅以及相关参数的正常范围。方法选择40例体格检查和纯音听阈、中耳分析结果正常且无眩晕发作史的健康志愿者,用500 Hz的click声刺激进行经眼外肌连接的前庭诱发肌源性电位(ocular-vestibular evoked myogenic potentials,oVEMPs)检查。结果 40名健康受试者均能引出稳定波形,引出率100%。n10潜伏期:左侧(9.76±0.48)ms,右侧(9.83±0.47)ms;振幅(6.34±0.39)μV。p15潜伏期:左侧(15.24±0.44)ms,右侧(15.14±0.45)ms;振幅(5.72±0.57)μV。n10的耳间振幅差比值0.02～0.29。结论 oVEMPs检查方法操作简单,用时短,不诱发眩晕,结果客观,可重复性好。

OBJECTIVE To explore the clinical value of the vestibular evoked myogenic potentials through the extraocular muscles,and determine the normal range of the latency and amplitude of the waveforms of the ocular vestibular evoked myogenic potentials.METHODS Forty healthy young volunteers without dizziness history were performed physical examination,pure tone threshold tests and middle ear analysis.The ocular vestibular myogenic potentials elicited from the external ocular were recorded on the surface beneath the infraorbital by 500Hz-click stimulating.RESULTS The stabilized waveforms werel recorded in all the forty volunteers.The average latency of wave n10 were（9.76±0.48）ms on the left side and（9.83±0.47）ms on the right side,and the average amplitude were（6.34±0.39）μV.The average potential of wave p15 were（15.24±0.44）ms on the left side and（15.14±0.45）ms on the right side,and the average amplitude were（5.72±0.57）μV.The interaural amplitude difference ratio of n10 were 0.02 to 0.29.CONCLUSION The detection of ocular-vestibular myogenic potentials elicited from the extraocular muscles were objective,easy and repeatable.Neither pain nor dizziness appeared during the detection.