颈中交感神经节阻滞治疗偏头痛临床应用

Clinical Application of the Middle Cervical Ganglion Block(MCGB) in the Treatment of Migraine

目的探讨颈中交感神经节阻滞(MCGB)治疗偏头痛的临床效果。方法偏头痛患者80例,随机分成A、B两组,每组40例。A组氟桂利嗪10 mg/d,睡前口服,连服2个月;B组患侧MCGB,1次/d,10次为一疗程,间隔1周进行第二疗程,共4个疗程。两个组治疗治疗前及治疗结束,利用经颅多普勒超声(TCD)检测脑血管、血流变化。治疗结束后,由不了解治疗方案的医生判断分析患者治疗效果。结果 A、B组治疗前脑血管血流异常率分别为80.0%、82.5%;治疗结束后脑血管血流异常率分别50.0%、12.5%;治疗结束后治愈(优)率分别为52%、90%,差异有统计学意义(P<0.05)。结论 MCGB能够有效纠正脑血管的舒缩功能失调,对偏头痛的治疗是一种简单、安全、有效的方法。

Objective To investigate the clinical effect of middle cervical ganglion block（MCGB） on the treatment of migraine.Methods In this series,80 migraine patients were randomly divided into two groups,with 40 cases each.In group A,flunarizine（FNZ） was given 10 mg a day,oral before bedtime and taking for 2 consecutive months.Group B was treated with MCGB,once per day,10 times for a period of course,total for 4 courses,one week interval between two courses.Transeranial color doppler（TCD） was used to measure the hemodynamic of brain before and after treatment in group A and B.Results In group A、and B,the abnormal rates of TCD were 80%,82.5% before treatment,and 50.0%,12.5% after treatment,the cure rate were 52%,90% after treatment,which showed significant difference（P0.05）.Conclusion MCGB can effectively correct the vasomotion function of the brain disorders.MCGB was simple,safe and effective in the treatment of migraine.