豆科药用植物中的抗肿瘤活性成分

Anti-tumor chemical constituents in the medicinal plants of Leguminosae

豆科(Leguminosae)植物在药用植物中占据重要地位,其化学成分类型丰富多样,且具有广泛的生物活性。近年来对该科药用植物的抗肿瘤活性研究较多,目前已经发现了一些活性较好的抗肿瘤活性成分,如甘草酸、甘草次酸以及苦参碱等。其中苦参碱已经应用于临床,且效果显著。因此,对该科植物进行抗肿瘤活性物质的研究意义重大。本文旨在概述豆科药用植物中抗肿瘤活性成分研究的最新成果及进展。

Leguminosae plants play an important role in the medicinal plants, in which diverse chemical compositions with a broad range of biological activities are isolated. An increasing attention has been paid to study their anti-tumor constitutes in the recent years. Several interesting compounds including glycyrrhizic acid, glycyrrhetic acid, matrine have exhibited significant anti-tumor activity, of which matrine has been used in clinic, and displayed a remarkable anti-tumor effect. This article will present a systematic overview of anti-- tumor chemical constitutes from this family.